What’s Methyl Salicylate?

What’s Methyl Salicylate?

Therefore, What Exactly Is Methyl Salicylate? An In Depth In Accordance With Menthol

Methyl salicylate is just an ester that is natural executes really much like menthol. It really is commonly removed through vapor distillation of wintergreen leaves.

Based on WebMD, methyl salicylate can be found in many topical ointments purchased throughout the countertop for small joint aches or muscular problems. It may be present in intimate services and products.

Therefore, what exactly is methyl salicylate and exactly what does it do? Both methyl and menthol salicylate are referred to as counterirritants, this means they cause cooling and warming feelings on your skin. Counterirritants are mainly responsible for the title, and response, known as “icy hot.”

A lot of these services and products shouldn’t be applied to younger kids due to toxicity issues, which we’ll discuss later in this essay.

Wintergreen Oil

You might be wondering, what exactly is methyl salicylate? You shall frequently hear about wintergreen“oil or oil of wintergreen.” Relating to a summary in the Journal of Alternative Complementary Medicine, methyl salicylate could be theprevalent ingredient within the oil and is additionally the purest kind in the greatest concentration you will definitely find. In accordance with an oil wintergreen podcast through the Royal community of Chemistry, oil of wintergreen contains 96-99% methyl salicylate. Through the exact same source, “…research indicates that methyl salicylate is component of the plant’s arsenal into the battle against pathogens and herbivores.”

Methyl salicylate smells really highly of mint. Regardless of this, it should additionally be noted that this element will not belong within the mint genus of plant types. The burning sensation that is cold triggered through the TRPA1 channel. Methyl salicylate additionally activates the warmth channel TRPV1, that will be exactly the same channel considered to be triggered by chilli peppers like capsaicin. Often, wintergreen oil is employed along with peppermint oil, considering that the two in tandem are considered to attenuate useful impacts. Wintergreen oil is acquired by steam distillation of this warmed, water-macerated leaves. It really is often utilized interchangeably with sweet birch oil for flavoring foods and sweets.

Certain Products Which Use Methyl Salicylate

Relating to drugs.com and goodguide.com, there are several products which contain methyl salicylate. Some products include…


Icy Hot Cream

Salonpas Soreness Patch

Analgesic Balm



Menthocin Patch with Lidocaine

Soothee Patch




CVS Mouth Rinse Natural Citrus

CVS Antiseptic Mouth Rinse

K-Y Yours+Mine Partners Lubricant

Jason Natural Cosmetics Dandruff Relief Treatment Shampoo

Forever Living Aloe Heat Cream

Colgate Peroxyl Antiseptic Oral Cleanser, Original

Orajel PM Toothache cream

CVS Extreme Strength Toothache relief

Young Living Thieves Dentarome Ultra Toothpaste

Eco-Dent Specialcare Toothpowders Tartarguard

Comparing Methyl Salicylate to Aspirin

One research posted in the Annals of Pharmacotherapy aimed to analyze the effectiveness of methyl salicylate in platelet inhibition when comparing to aspirin. Platelet aggregation is another means of talking about platelets clumping together when you look at the bloodstream. This really is pertaining to bloodstream clotting.

This research utilized a sample that is small of healthier guys into the 30-46 age groups. All individuals got 162 mg of aspirin before a washout period and then 5 g of 30% methyl salicylate preparation, both to be utilized on the anterior legs. It had been discovered that “both aspirin and MS produced statistically platelet that is significant; aspirin decreased the AUC from 183; 139 to 292 to 85; 48 to 128 (p = 0.008) and MS decreased the AUC from 197; 118 to 445 to 112; 88 to 306 (p = 0.011).”

There clearly was no difference that is large the 2. This implies that methyl salicylate works because effortlessly as aspirin for platelet aggregation, at minimum in healthier people.

Poisoning Fables and Issues

Research with this substance on the net will expose a small number of instance reports of infant death. a things that are few be noted about these. Such infant fatalities usually included the accidental swallowing of pure oil of wintergreen, the concentration that is highest of methyl salicylate you will get.

This does not mean that overdoses can only just take place with ingestion; the substance may be absorbed through the skin then incorporated into one’s system. Nevertheless, it absolutely was found in “Toxicity fables: the particular danger of Essential Oil Use,” published in the Overseas Journal of Aromatherapy, that, “if 10?ml of a 2.5% formula of wintergreen oil were to be reproduced all simultaneously to the skin and completely consumed, the dose would express exactly the same amount of salicylate present in one single 325?mg aspirin tablet.”

For this reason oil of wintergreen is cbd regarded as to be fairly low-risk with few effects that are side. Nevertheless, it is strongly recommended that brand brand new moms and dads avoid obtaining the substance when you look at the household, in the off-chance that a child might get their or her arms upon it.

Additionally, it’s well worth noting that methyl salicylate happens to be limited to be used in cosmetics in Canada.

Trace Quantities Are Contained In Hemp Seed Oil

Among numerous health great things about hemp seed oil constituents, you may want to find trace amounts of methyl salicylate. Hemp seed oil’s fatty acid content (omega-3s and omega-6s) is noticably as a health plus. The oil additionally contains 10-15% fiber, 20-25% protein, and 20-30% carbs.

A bioassay posted in “The structure of Hemp Seed Oil as well as its Possiblebeing a essential way to obtain nutrition” reported from the methyl salicylate content of hemp seed oil. In addition they reported on the other side things contained in hemp seed oil, such as for instance cannabidiol, ?-Sitosterol, tocopherols, and terpenes and terpenoids.

To Conclude

So let’s review what we’ve learned therefore far:

Methyl salicylate is just an ester that is natural may be made naturally or synthetically into the lab it is often extracted via vapor distillation of wintergreen leaves.

Oil of wintergreen may be the strongest, purest concentration of methyl salicylate.

TRY NOT TO INGEST oil of wintergreen.

Methyl salicylate can also be present in over-the-counter services and products such as for instance toothache ointments and muscle tissue discomfort relievers to alleviate pain and create a soothing feeling. It’s also sometimes found in a small amount to flavor meals and candies.

Wintergreen oil placed on your skin in the right doses can express the same quantity of salicylate present in one 325 mg aspirin tablet.

Methyl salicylate works effortlessly against platelet aggregation—about as much as aspirin does.

Methyl salicylate can be found in hemp seed oil in trace quantities.

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